Assessment of antibacterial activity of some extracts of Securinega virosa (Roxb. ex Willd.) Baill on pathogens bacteria

نویسندگان

چکیده

Today, faced with the emergence of microbial resistance to antibiotics, renewal arsenal anti-infective drugs is acutely posed. In order explore other sources drugs, this study therefore proposed evaluate antibacterial activity in vitro several extracts Securinega virosa, a well-known combretacea populations northern Côte d'Ivoire. To achieve objective, method determining diameters zones inhibition on wells an agar medium as well that minimum inhibitory concentration (MIC) and bactericidal were carried out. The results showed aqueous extract was not active all bacteria tested. dichloromethane fraction at 500 mg/mL inhibited growth Shigella Typhi (12.5 mm), followed by Streptococcus sp. (12.33 0.25 mm) Staphylococcus aureus Meti-R (11.75 1.25 mm). ethyl acetate primarily Gram-positive average 12 mm mg/mL. ethanol most ranging from 9 13.33 It lowest MIC (3.12 mg/mL) gram-positive large Gram-negative levels 12.5 50 This through its provides data favor traditional use virosa therapy.
 Keywords : vitro, antibacterial,

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ژورنال

عنوان ژورنال: Journal of Drug Delivery and Therapeutics

سال: 2023

ISSN: ['2250-1177']

DOI: https://doi.org/10.22270/jddt.v13i1.5726